BAGIM is an active community of Boston area scientists bringing together people from diverse fields of modeling and informatics to impact life and health sciences. BAGIM strives to create a forum for great scientific discussions covering a wide range of topics including data management, visualization, computational chemistry, drug discovery, protein structure, molecular modeling, structure-based drug design, data mining, software tools, and the sharing of goals and experiences. Our community is made up of participants from academia, government, and industry whose goal is to engage in the discussion of science involving a synthesis of theory and technology. Discussions sponsored by BAGIM are targeted to the needs and interests of informatics scientists, computational chemists, medicinal chemists, and statisticians. BAGIM also provides opportunities for networking within these disciplines as well as an arena for the dissemination of information of specific interest to the membership.

Wednesday, August 8, 2018

Illuminating the Druggable Genome (IDG) Outreach with BAGIM

IDG Outreach meeting with BAGIM
9 am – 2 pm, August 23, 2018
Harvard Medical School
Boston, MA

RSVP Email: idg.rdoc@gmail.com before August 19th, or you will not be able to enter the building.
Come and hear more about Illuminating the Druggable Genome Consortium, a NIH Common Fund program,
composed of Knowledge Management Centers (KMC), Data Resource Generating Centers (DRGC), and
Resource Dissemination and Outreach Center (RDOC).


9:00 Welcome and Introduction - Tudor Oprea, PhD, MD

9:05 Presentation from KMC at University of New Mexico (UNM)
Protein Knowledge Graphs and Machine Learning for
Target Prioritization - Tudor Oprea, PhD, MD

9:30 Presentation from KMC at Icahn School of Medicine at Mt.
Sinai (ISMMS)
Harmonizome-ML: Interactive On-the-Fly Imputation of
Knowledge about Genes and Proteins with Machine
Learning - Avi Ma'ayan, PhD

9:55 Presentation from KMC at National Center for Advancing
Translational Sciences (NCATS)
Pharos, User-Interface to Illuminating Druggable Genome -
Dac-Trung Nguyen and Timothy Sheils

10:20 Break

10:35 Presentation from DRGC - Kinase
Dark Kinase Knowledgebase - Matthew Berginski, PhD
(UNC at Chapel Hill)
Small Molecule Library Informatics - Nienki Moret, Bsc

11:25 Presentation from DRGC - Ion Channel
Data driven co-ablation of Ion Channels - Zicheng Hu, PhD

11:50 Break

12:20 Presentation from outside IDG community
Functional and structural interactions in druggable targets
from evolutionary information - Chris Sander, PhD
Genetic variation in human drug-related genes - Debora
Marks, PhD (Harvard)

13:10 Feedback loop: Discussion on improvements to better
serve the community.

Harvard Medical School
Warren Alpert Building, Room 563
200 Longwood Avenue
Boston, MA 02115

**Attendees**: Please email your name and affiliation to idg.rdoc@gmail.com by August 19, 2018 in order to

pass HMS building security.
BAGIM - Boston Area Group for Informatics and Modeling